Sheet Pan Chicken Muffaletta
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If you love the bold, briny flavors of a classic muffaletta sandwich, this easy Muffaletta Chicken Sheet Pan Dinner turns those flavors into a simple weeknight meal. Made with juicy chicken thighs, tender roasted cauliflower, olive salad, salami, roasted peppers, and fresh greens, it's a flavorful one-pan dinner with very little prep.
This sheet pan dinner takes inspiration from my sheet pan chicken and sweet potatoes with Caesar salad greens and my Greek chicken sheet pan recipe.

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Inspired by the beloved New Orleans sandwich, this recipe keeps all the signature muffaletta flavor while transforming it into an easy dinner idea. And because the warm olive mixture lightly dresses the greens right on the sheet pan, every bite is savory, bright, and full of texture.
Recipe Overview
This muffaletta chicken recipe is an easy sheet pan dinner made with chicken thighs, cauliflower, olive salad, salami, roasted red peppers, and fresh greens. It has all the bold flavors of a muffaletta sandwich in a lighter, weeknight-friendly meal that comes together mostly in one pan.
What I Love About This Recipe
This is the kind of dinner recipe I love on busy evenings. It feels interesting and full of flavor, but the prep is wonderfully simple.
What makes it especially good is the way the classic muffaletta ingredients become a warm, savory topping for the roasted chicken and cauliflower. The olive salad, salami, and roasted peppers add so much flavor with very little effort, and when the greens are tossed in at the end, they soak up all those delicious pan juices.
It's also flexible. You can serve it straight from the pan as a complete meal, or tuck leftovers into bread for a muffaletta-inspired sandwich the next day.
For more easy ideas, see our sheet pan recipes collection.
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Ingredients
Like many sheet pan dinners, the beauty of this recipe is in its simplicity. A handful of pantry seasonings, a jar of olive salad, roasted red peppers, and a few fresh herbs turn chicken thighs and cauliflower into a dinner with bold muffaletta flavor and very little prep.

Chicken and Vegetables
- Boneless skinless chicken thighs: Juicy, flavorful, and perfect for roasting on a sheet pan.
- Cauliflower florets: Roast beautifully and absorb all the savory, briny flavors in the pan.
Seasonings
- Dry mustard
- Paprika: Use smoked paprika for deeper flavor or sweet paprika for a milder finish.
- Garlic powder
- Dried oregano
- Olive oil
These simple pantry seasonings give the chicken and cauliflower a savory base that works beautifully with the muffaletta-inspired toppings.
Muffaletta-Inspired Topping
- Italian olive salad: A jarred olive salad makes this recipe quick and easy. Drain and rinse lightly if needed.
- Genoa salami: Adds richness and that signature muffaletta flavor.
- Jarred roasted red peppers: Sweet, tender, and easy to keep on hand.
- Red wine vinegar: Brightens everything and ties the topping together.
Greens and Fresh Herbs
- Mixed greens: Romaine, arugula, or spring greens all work well.
- Fresh herbs: Basil, dill, parsley, and oregano all add freshness and color.
How to Make Muffaletta Chicken

- Step 1: Preheat the oven to 425°F. Place the chicken thighs and cauliflower florets on a large sheet pan. Drizzle with olive oil and season with salt, pepper, dry mustard, paprika, dried oregano, and garlic powder. Toss to coat well, then arrange the cauliflower in the center of the pan and the chicken around the edges.

- Step 2: Bake for 25 to 30 minutes, or until the chicken is deeply golden and cooked through, registering 165°F in the thickest part, and the cauliflower is tender.

- Step 3: While the chicken roasts, combine the drained olive salad, salami, roasted red peppers, and red wine vinegar in a medium bowl. In a separate bowl, gather the mixed greens and fresh herbs.

- Step 4: Remove the sheet pan from the oven. Scatter the olive salad mixture over the cauliflower and gently stir to combine. Return to the oven for 5 minutes, or until warmed through. Remove from the oven and toss in the greens and herbs. The warmth from the pan will slightly soften the greens and lightly dress them with all the flavorful juices.
Hint: Drain the olive salad well so the sheet pan doesn't become too wet. If your olive salad tastes especially salty or oily, a quick rinse and drain helps keep the finished dish balanced.
Variations
- Use olives instead of olive salad: If you don't have jarred olive salad, use a mix of chopped green and black olives with a little olive oil, minced giardiniera, and capers.
- Swap the vegetable: Broccoli or wedges of red onion would also work well here.
- Use chicken breasts: Boneless skinless chicken breasts can work, although thighs tend to stay juicier.
- Add provolone for serving: For an even more muffaletta-inspired finish, tuck slices of provolone alongside the chicken when serving.
- Make it spicier: Add red pepper flakes or a spoonful of the hot vegetables from the olive salad.
Serving Suggestions
This recipe is delicious served straight from the sheet pan as a complete dinner, with the chicken, cauliflower, and greens all layered together on plates.
For sides, you could add:
- crusty bread
- roasted potatoes
- a simple white bean salad
- extra greens with a splash of red wine vinaigrette
For dessert, try these classic New Orleans Pecan Praline Cookies

Turn It Into a Sandwich
This recipe is also wonderful as a sandwich. Layer the chicken, cauliflower, and olive mixture into sturdy bread for a weeknight version of a muffaletta-inspired sandwich.
The best bread for a traditional muffaletta is a round sesame-topped Italian loaf that's crusty on the outside yet soft enough to absorb the flavorful juices. When that's hard to find, focaccia, ciabatta, or a soft Italian loaf are all excellent alternatives.

Recipe FAQs
A muffaletta is a classic New Orleans sandwich traditionally made with round Italian bread, olive salad, Italian meats, and cheese. This recipe borrows those bold, signature flavors and turns them into an easy sheet pan chicken dinner.
It's both. This recipe uses the flavors of a muffaletta-olive salad, salami, roasted peppers, herbs, and tangy dressing-but serves them as a sheet pan chicken dinner instead of a sandwich.
Romaine and arugula are both excellent here. Romaine stays crisp and hearty, while arugula adds a peppery bite. A spring mix can also work for a softer finish.
That depends on the brand and how assertive the flavor is. If it seems especially oily or salty, a quick drain and light rinse can help keep the flavors balanced.
You can prep the olive mixture and chop the cauliflower ahead of time. For best texture, roast the chicken and vegetables just before serving.

Muffuletta Chicken Sheet Pan Dinner
Equipment
Ingredients
- 2 tablespoons olive oil
- 4 boneless skinless chicken thighs
- 1 head cauliflower chopped into large (2-inch) florets (about 5 cups)
- 1½ teaspoons salt or 2 teaspoons kosher salt
- 1 teaspoon dry mustard
- 1 teaspoon paprika (smoked or sweet)
- ½ teaspoon garlic powder
- ½ teaspoon dried oregano
- ½ teaspoon black pepper
- 4 cups mixed greens like romaine or arugula
- 1 cup mixed herbs basil, dill, parsley
- 1 16-oz jar Italian olive salad (such as Mezzetta), drained and rinsed or a jar of your favorite olives
- 3 oz. Genoa salami cut into ½-inch chunks (about ½ cup)
- ½ cup sliced roasted red bell peppers from 1 [16-oz.] jar, drained
- 1 tablespoon red wine vinegar
- Chopped fresh oregano
Instructions
- Preheat oven to 425° F.
- Place the chicken and cauliflower florets on a baking sheet. Drizzle with olive oil and sprinkle with salt, dry mustard, paprika, pepper, dried oregano, and garlic c powder. Turn to coat the chicken and cauliflower. Place the cauliflower in the center of the pan and the chicken along the edges.
- Bake until the chicken is deeply golden, and a thermometer inserted into the thickest part of the chicken registers 165℉, and the cauliflower is tender, about 25-30 minutes.
- For the Olive Salad: Combine sliced salami, roasted red bell peppers, and vinegar in a medium bowl.
- For the salad, combine the lettuce greens and fresh herbs, like oregano.
- Remove the sheet pan from the oven. Scatter the olive salad mixture over the cauliflower and stir to combine. Bake until heated through, about 5 minutes. Remove, toss in the greens, garnish with fresh oregano or herbs and serve.
- Serving Ideas: Make a sandwich. The best bread for a muffuletta is a 10-inch round, crusty yet soft Italian bread topped with sesame seeds. A sturdy bread with an airy texture is perfect for absorbing the olive oil and meats. When authentic NOLA bread is unavailable, focaccia, ciabatta, or soft Italian loaves are excellent alternatives.
Notes
- Olive Salad: For the best flavor balance, drain the olive salad well. If it seems especially oily or salty, give it a quick rinse and drain again before using.
- Greens: Romaine and arugula are both great choices for the greens. Romaine stays crisp, while arugula adds a peppery bite.
- Seasoning: Smoked paprika adds a deeper flavor, but sweet paprika works well too.
- Cauliflower: Cut the cauliflower into large florets so it roasts without becoming too soft.
- Serving Ideas: This recipe is also delicious served sandwich-style on crusty Italian bread, focaccia, or ciabatta.
Nutritional information is only an estimate. The accuracy of the nutritional information for any recipe on this site is not guaranteed.
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My family loves all the flavors in this easy sheet pan chicken recipe. I love that the prep is minimal; it's versatile for sandwiches, bowls, and salads. Plus, the flavors are incredible!